Ugbajo Itsekiri USA Inc. is a non-profit organization registered in the United States with its headquarters in Washington, D.C. Currently made of ten regional affiliates from various states in the United States its mission is to promote Itsekiri culture, custom and heritage; unity and cordiality among Itsekiri people; peaceful coexistence between Itsekiri and their host in the Unites States of America and their neighbors in Nigeria; support and promotes social and economic development for Itsekiri and their homeland.

All members of the regional affiliate associations are Itsekiri. Ugbajo Itsekiri USA Inc., and its affiliates are publicly funded charitable organizations that provide humanitarian services in Nigeria and the United States.